Study Design

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Multicenter, prospective, randomized single blind crossover study

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18 patients currently experiencing pain upon infusion enrolled

18 pts.

Pt. 1

Pt. 2

Pt. 3

Etc.

Random Allocation

A

A

B

B

C

C

A

B

A

B

C

C

C

A

B

C

B

A

A.

Bicarbonate 38mM, 3.86% glucose, pH 7.4

B.

Bicarbonate/lactate 25/15 mM, 3.86% glucose, pH 7.4

C.

Diana 3.86% glucose, pH 5.2

Six single dwells (1-3 weekly)

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