IRMA 2Study design

Double-blind treatment

Screening/Enrollment

590 patients with type 2 diabetes,

microalbuminuria (albumin excretion rate 20 – 200 ?g/min),

normal renal function, and hypertension

Up to 5 weeks

Irbesartan 150 mg

Follow-up: 2 years

Placebo

Irbesartan 300 mg

Parving H-H et al. N Engl J Med 2001;345:870–8.

IRMA 2 Study design