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Número: 095 Siguiente resumen: Com096

Adrenal Myelolipoma in a patient with Agnogenic Myeloid Metaplasia.

Remitido por: Andréa Rodrigues Cordovil Pires, Luciana Wernersbach Pinto. :

Departament of Pathology, Fluminense Federal University, Niterói, Brazil. Rua Marquês do Paraná, 303 Niterói - RJ - Brasil - CEP:24.030-210

Correo electrónico: andrea@microlink.com.br
Agnogenic myeloid metaplasia is an uncommon chronic myeloproliferative syndrome characterized by pluripotent stem cell neoplastic proliferation, myelofibrosis, osteosclerosis and extramedullary hematopoiesis. The liver and spleen are the most common sites of extramedullary hematopoiesis, and it's seen as three lineage hematopoietic islands in sinusoids with varying degrees of pericellular fibrosis associated. Myelolipoma is a rare, endocrinally non-functional benign neoplasm, of unknown origin, usually affecting adrenal gland. It is characterized by a mixture of mature fat tissue and tipical hematopoietic cells, without relation with diseases causing extramedullary hematopoiesis. It is usually a radiologic, surgery or autopsy finding. We report the first known case of association of myelolipoma and agnogenic myeloid metaplasia in an autopsy case and discuss if it is a extremely rare coincidence or if there is some relationship between them. ------------------------------------------------------------------------ Dra. Andréa Rodrigues C. Pires is pathology professor at Fluminense Federal University and works with autopsy, hematopathology and informatics. Dra. Luciana Wernersbach Pinto is pathology resident at Fluminense Federal University. ------------------------------------------------------------------------ Antônio Pedro Universitary Hospital is a public hospital situated in Niterói, the 4 th. city in life quality in Brazil. It has more than a million habitants an is less than 15 Km away from the city of Rio de Janeiro.

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