Diapositiva PPT

enzymes

Receptors

Angiotensinogen

renin

Angiotensin(1-10) A-I

ACE

Chymase, catepsins AT 2

Angiotensin (1-8) A-II AT 1

nephrilysin

carboxipeptidase

thimet oligopep.

Angiotensin 1-9

nephrilysin

Prolyl - carboxipeptid.

aminopeptidaseA

Angiotensin 1-7

Angiotensin 2-8 (A III)

AT ?

Angiotensin 3-8 (A IV)

AT 4

aminopeptidases

endopeptidases

aminopeptidases

endopeptidases

aminopeptidases A,M

Hilgers & Mann, JASN 2002; 13:1100-08

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