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Notas:
Unmet clinical need associated with abdominal obesity
Abdominal obesity (measured by high waist circumference) represents a major health threat, as it often presents in association with a cluster of cardiometabolic risk factors.
Indeed, 86% of abdominally obese subjects have one or more cardiovascular risk factors, and 24% have at least two additional cardiovascular risk factors that identify them as having the metabolic syndrome.1
Clearly, abdominal obesity signifies a marked increase in overall cardiovascular risk that is often driven by the progression of multiple risk factors.
New approaches to the management of cardiovascular risk that address this complex pathophysiology are needed.
1. NHANES 1999–2000. http://www.cdc.gov/nchs/nhanes. Data downloaded September 2004 using SAS software (Data on file)
