Purkinje cell hamartoma (Histiocytoid
cardiomyopathy). Study of a case in an 18 months infant.
Marcial Garcia-Rojo, Carlos Gamallo, Felipe
Moreno
[Title] [Introduction] [Results]
[Pictures] [Discussion]
[Bibliography]
Materials & Methods
- He have studied a 18 months old female infant that
presented in 1987 with a clinical picture of shock and
tachycardia of 320 beats per minute, resistant to medical
treatment. She was then treated surgically, with a
resection of a whitish area in the left interventricular
septum. This area extended from the apex of the left
ventricle until the outflow tract.
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- The patient has remained asymptomatic since the
intervention, until the last revision in 1997.
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Pathological procedures
- The specimen received for histological study was fixed in
buffered 10 % formalin and stained with
Hematoxylin-Eosin, Masson trichrome and Orcein. A part of
the formalin fixed specimen was post-fixed in 4 %
glutaraldehyde and it was processes with the routine
technique for electron microscopy.
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- Paraffin-embedded tissue sections were stained
immunohistochemically by the avidin-biotin technique,
with policlonal (actin, myosin, alpha-actinin,
tropomyosin, calmodulin, factor VIII, collagen IV,
laminin, and S-100) and monoclonal (desmin and vimentin )
antibodies.
