  
         | 
        Bone marrow tissue from biopsy
        specimen. It shows marked cellularity, with a moderate
        increase in megakaryocyte number, many of them
        atypical.HE, 40x. 
         | 
    
    
            | 
        Bone marrow tissue from biopsy specimen. It shows
        marked cellularity, with a moderate increase in
        megakaryocyte number, many of them atypical,
        hyperlobulated and hyperchromatic.There is also a
        hyperplastic left shift of the myeloid lineage and some
        increase in connective tissue. HE, 40x. | 
    
    
          | 
        Liver tissue from autopsy. It shows hematopoietic
        islands inside sinusoids, predominantly with myeloid and
        erithroid lineages. There are also scattered
        megakaryocytes in other areas not shown.There is no
        fibrosis. HE, 40x. | 
    
    
          | 
        Spleen tissue from autopsy. It shows hematopoietic
        islands in red pulp, predominantly with myeloid and
        erithroid lineages. There are also scattered
        megakaryocytes in other areas not shown.There is no
        fibrosis. HE, 40x. |