Comunicación Nº 096 English version English version

Cambios del microambiente tímico en la sífilis congénita humana

Eliene C. Fonseca, Mônica P. Almeida, Évlin H. Maia, Dora M. F. Menezes and Wilson Savino*

[Título] [Introducción] [Material y Métodos] [Resultados] [Iconografía][Discusión] [Bibliografía]

Discusión

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BIBLIOGRAFÍA

  1. Aguilar LK, Aguilar-Cordova E, Cartwright J Jr & Belmont JW : Thymic nurse cells are sites of thymocyte apoptosis.J. Immunol 152 : 2645, 1994.
  2. Anderson SJ & Perlmutter RM : A signaling pathway governing early thymocyte maturation. Immunol. Today 16(2) : 99, 1995
  3. Asma GEM, Van Den Bergh & Vossen JM : Use of monoclonal antibodies in a study of the development of T lymphocytes in the human fetus. Clin. Exp. Immunol. 53 : 429, 1983.
  4. Baughn RE, McNeely MC, Jorizzo JL & Musher DM : Characterization of the antigenic determinants and host components in immune complexes from patient with secondary syphilis. J. Immunol. 136(4) : 1406, 1986.
  5. Baughn RE: Role of fibronectin in the pathogenesis of syphilis. Rev. Inf. Dis. 9(suppl.4) : 374, 1987.
  6. Berrih S, Savino W & Cohen S : Extracellular matrix of the human thymus: immunofluorescense studies on frozen sections and cultured epithelial cells. J. Histochem. Cytochem. 33(7) : 655, 1985.
  7. Boyd R.L. & Hugo P.: Towards an integrated view of the thymopoiesis. Immunol. Today 12: 71, 1991.
  8. Boyd R.L., Tucek C.L., Goldfrey D.I., Izon D.J., Wilson T.J., Davidson N.J., Bean A.G.D., Ladyman H.M., Ritter M.A. & Hugo P.: The thymic microenvironment. Immunol. Today 14(9): 445, 1993.
  9. De Souza M., Tilney N.L. & Kupiec-Weglinski J.W. : Recognition of self within self specific lymphocyte positioning and extracellular matrix. Immunol. Today 12: 262, 1991.
  10. Fitzgerald TJ, Repesh LA, Blanco DR & Miller JN: Attachment of treponema pallidum to fibronectin, laminin, collagen IV and Collagen I, and blockage of attachment by immune rabbit IgG. J. Vener. Dis. 60: 357, 1984
  11. Fitzgerald TJ & Repesh LA: Interactions of fibronectin with Treponema pallidum. Genitourin. Med. 61: 147, 1985
  12. Fonseca E.C., Chammas R., Brentani R.R. & Savino W. : Co-cultures of fibroblats and epithelial cell lines: a model to study thymocyte-stromal cell interactions. 2nd Brazilian Symposium on Extracellular Matrix (Resumos).Campos do Jordão-SP, 1992.
  13. Fonseca E.C., Villa-Verde D.M., Lannes-Vieira J. & Savino W. : Thymic extracellular matrix in Down’s syndrome. Braz. J. Med. Biol. Res. 22: 971, 1989.
  14. Haynes BF : The role of the thymic microenvironment in promotion of early stages of human T cell maturation. Clin. Res. 34: 422, 1986.
  15. Krugman S, Katz SL, Gershon AA & Wilfert CM: Sexually transmittable diseases in children. In Infectious Diseases of Children, 9th edition, 1992.
  16. Lannes-Vieira J, Cirne-Lima EO & Savino W : Hidrocortisone modulates cytokeratin and extracellular matrix expression by the thymic microenvironment. Ann. N. Y. Acad Sci. 650: 85, 1992.
  17. Lannes-Vieira J, Vanier-Santos M, Brentani RR & Savino W : Intra-thymic modulation of the CD3 complex and T cell receptor expression by in vivo injection of anti-fibronectin antibodies. In press.
  18. Lannes-Vieira J, Van der Meide PH & Savino W : Extracellular matrix components of the mouse thymic microenvironment. II. In vitro modulation of basement membrane proteins by interferon-gamma: relationship with thymic cell proliferation. Cell Immunol. 137 : 1, 1991.
  19. Le PT, Kurtzberg J, Brandt SD, Niedel JE, Haynes BF & Singer KH : Thymic epithelial cell produce granulocyte and macrophage colony stimulating factors. J. Immunol. 141 : 1211, 1988.
  20. Martin-Fontecha A, Schuurman HJ & Zapata A : Role of thymic stromal cells in thymocyte education : A comparative analysis of different models. Thymus 22: 201, 1994.
  21. Meireles-de-Souza L.R., Trajano V. & Savino W. : Is there an interspecific diversity of the thymic microenvironment? Dev. Immunol. 2: 51, 1992.
  22. Montes GS & Junqueira LCU: The use of the Picrosirius - polarization method for the study of the biopathology of collagen. Mem. Inst. Oswaldo Cruz, 1992.
  23. Numazaki K., Goldman H., Bai X.-Q., Wong I. & Wainburg M.A. : Effects of infection by HIV-1, cytomegalovirus and human measles virus on cultured human epithelial cells. Microbiol. Immunol. 33(9): 733, 1989.
  24. Ocampo-Lyra J.S.P., Madi K., Maeda C.T. & Savino W.: Thymic extracellular matrix in human malnutrition. J. Pathol, 171(3) : 231, 1993.
  25. Ouaissi MA: Role of RGD sequence in parasite adhesion to host cells. Parasitol. Today 4: 169, 1988.
  26. Owen JJT & Moore NC : Thymocyte-stromal-cell interactions and T-cell selection. Immunol Today 16(7) : 336, 1995.
  27. Reza JN & Ritter MA : Differential expression of adhesion molecules within the human thymus. Dev. Immunol. 4: 55, 1994
  28. Ritter M.A. & Boyd R.L.: Development in the thymus: It takes two to tango. Immunol. Today 14(9): 462, 1993.
  29. Savino W.: The thymic microenvironment in infectious diseases. Mem. Inst. Oswaldo Cruz 85: 255, 1990.
  30. Savino W &Berrih S: Thymic extracellular matrix in myasthenia gravis. Lancet ii : 65, 1984.
  31. Savino W., Dardenne M., Marche C., Trophilme D., Dupuy J-M., Pekovic D., Lapointe N. & Bach J-F.: Thymic epithelium in AIDS: an immunohistologic study. Am. J. Pathol. 122: 302, 1986.
  32. Savino W & Dardenne M : Imunne-neuroendocrine interactions. Immunol. Today 16(7) : 318, 1995.
  33. Savino W & Dardenne M : Thymic hormones containing cells. IV- Immunohistology evidence for the simultaneous presence of thymulin, thymopoietin and thymosin alfa-1 in normal and pathological human thymus. Eur. J. Immunol. 14: 987, 1984.
  34. Savino W. & Lannes-Vieira J.: Is there a role for extracellular matrix in thymus physiology and pathology? Mem. Inst. Oswaldo Cruz 86 suppl 3: 109, 1991.
  35. Savino W., Leite de Morais M.C., Silva Barbosa S.D., Fonseca E.C., Cotta-de-Almeida V. & Hontebeyrie-Joscowics M.: Is the thymus a taget organ in infectious diseases? Mem. Inst. Oswaldo Cruz, 87(suppl.5) : 73, 1992.
  36. Savino W., Villa-Verde D.M. & Lannes-Vieira J.: Extracellular matrix proteins in intrathymic T-cell migration and differentiation. Immunol. Today 14(4): 158, 1993.
  37. Shimizu Y & Shaw S : Lymphocyte interactions with extracellular matrix. FASEB J. 5: 2292, 1991
  38. Schuppan D & Rugl M : Matrix in signal transduction and growth factor modulation. Brazillian J. Med. Biol. Res. 27 : 2125, 1994.
  39. Singer K.H. & Haynes BF : Epithelial and thymocyte interactions in human thymus. Human Immunol. 20: 127, 1981.
  40. Singer K.H. & Haynes BF : Interactions between epithelial cells and T lymphocytes: role of adhesion molecules. J. Leuk. Biol. 48 : 367, 1990
  41. Sutsumi K., Sawada M., Narumiya S., Nagamine J., Sakata T., Iwagami S., Kita Y., Teraoka H., Hirano H., Agata M., Hamaoka T. & Fugiwara H. : Adhesion of immature thymocyte to thymic stromal cells though fibronectin molecules and its significance for the induction of thymocyte differentiation. Proc. Natl. Acad. Sci. USA 88: 5685, 1991.
  42. Van-Baarlen J, Schuurman HJ & Huber J : Acute thymus involution in infancy and childhood: a reliable marker for duration of acute illness. Hum. Pathol. 19(10) : 1155, 1988.
  43. Villa-Verde DM, Lagrota-Candido JM, Vannier-Santos MA, Chammas R, Brentani RR & Savino W : Extracellular matrix components of the mouse thymus microenvironment. IV- Modulation of thymic nurse cells by extracellular matrix ligands and receptors. Eur. J. Immunol. 24(3) : 659, 1994.
  44. Villa-Verde DM & Savino W : Thymic "nurse" cells express extracellular matrix proteins. Mem. Inst. Oswaldo Cruz 86(suppl.3) : 109, 1991

 

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